The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 08, 2020
Filed:
Jan. 27, 2017
Paris Sciences ET Lettres-quartier Latin, Paris, FR;
Centre National DE LA Recherche Scientifique, Paris, FR;
Inserm (Institut National DE LA Santé ET DE LA Recherche Médicale), Paris, FR;
Printnet Ltd., Budapest, HU;
Zsolt Lenkei, Les Molières, FR;
András Málnási Csizmadia, Budapest, HU;
Miklós Képiró, Siklos, HU;
Boglárka Várkuti, Balatonalmadi, HU;
PARIS SCIENCES ET LETTRES-QUARTIER LATIN, Paris, FR;
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, Paris, FR;
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), Paris, FR;
PRINTNET LTD., Budapest, HU;
Abstract
The present invention relates to highly soluble, non-fluorescent and photostable myosin inhibitors; especially, for in vivo inhibition of the ATPase activity of neuronal non-muscle myosin 2 of formula (II): wherein Q, Q, Q, Q, R, R, Rand Rare as defined in claim. The invention also relates to pharmaceutical compositions or medicaments comprising the compounds of the invention and processes for manufacturing these compounds and their intermediates.