The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 08, 2020

Filed:

Jul. 07, 2017
Applicants:

Universite Catholique DE Louvain, Louvain la Neuve, BE;

Cliniques Universitaires Saint-luc, Brussels, BE;

Inventors:

Denis Dufrane, Wavre, BE;

Christian Delloye, Wezembeek-Oppem, BE;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/38 (2006.01); A61L 27/36 (2006.01); C12N 5/0775 (2010.01); C12N 5/077 (2010.01);
U.S. Cl.
CPC ...
A61L 27/3821 (2013.01); A61L 27/3608 (2013.01); A61L 27/3817 (2013.01); A61L 2430/02 (2013.01); C12N 5/0653 (2013.01); C12N 5/0667 (2013.01);
Abstract

Biomaterial having a multi-dimensional structure and comprising demineralized bone matrix dispersed within differentiated mesenchymal stem cells (MSCs) tissue, wherein MSCs are adipose tissue-derived stem cells. Method for producing this biomaterial comprising incubating MSCS in osteoblastic and/or chondrongenic medium in presence of demineralized bone matrix. Use of this biomaterial for alleviating or treating a bone or cartilage defect, supporting or correcting a congenital or acquired abnormality, supporting a bon or articular bone replacement following surgery or trauma, and/or supporting a musculoskeletal implant.


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