The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 08, 2020

Filed:

Jan. 08, 2018
Applicant:

The George Washington University, Washington, DC (US);

Inventors:

Haitao Cui, Arlington, VA (US);

Wei Zhu, Washington, DC (US);

Lijie Grace Zhang, Washington, DC (US);

Assignee:

The George Washington University, Washington, DC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/38 (2006.01); A61L 27/50 (2006.01); A61L 27/52 (2006.01); A61F 2/06 (2013.01); A61L 27/16 (2006.01); A61L 27/18 (2006.01); B29C 64/209 (2017.01); B33Y 10/00 (2015.01); B33Y 30/00 (2015.01); B29C 64/118 (2017.01); A61L 27/22 (2006.01); B29C 64/135 (2017.01); B33Y 70/00 (2020.01);
U.S. Cl.
CPC ...
A61L 27/16 (2013.01); A61L 27/18 (2013.01); A61L 27/222 (2013.01); A61L 27/3808 (2013.01); A61L 27/3826 (2013.01); A61L 27/507 (2013.01); A61L 27/52 (2013.01); B29C 64/118 (2017.08); B29C 64/209 (2017.08); B33Y 10/00 (2014.12); B33Y 30/00 (2014.12); A61F 2/062 (2013.01); A61L 2430/22 (2013.01); B29C 64/135 (2017.08); B33Y 70/00 (2014.12);
Abstract

A coaxial needle having two or more passageways for forming a biomimetic bioprinted blood vessel tubular construct. The coaxial needle has an external needle passageway and an internal needle passageway separated by an internal barrier, and having a nozzle at an end thereof. A bioink is provided flowable through the external needle passageway and a crosslinking solution is provided flowable through the internal needle passageway. The crosslinking solution contacts the bioink as the crosslinking solution and bioink exit the nozzle thereby forming a tubular blood vessel construct.


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