The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 08, 2020
Filed:
Jun. 01, 2016
Applicant:
The Johns Hopkins University, Baltimore, MD (US);
Inventors:
Xing Yang, Baltimore, MD (US);
Il Minn, Ellicott City, MD (US);
Steven Rowe, Parkville, MD (US);
Sangeeta Ray, Ellicott City, MD (US);
Ronnie C. Mease, Fairfax, VA (US);
Michael Gorin, Towson, MD (US);
Mohamad Allaf, Baltimore, MD (US);
Martin G. Pomper, Baltimore, MD (US);
Assignee:
The Johns Hopkins University, Baltimore, MD (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/04 (2006.01); C07D 417/14 (2006.01); C07D 417/12 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 51/0497 (2013.01); A61P 35/00 (2018.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01);
Abstract
Highly potent and selective radionuclide-based imaging and therapy agents targeting carbonic anhydrase IX with minimum non-specific organ uptake are disclosed. Methods of imaging and/or treating carbonic anhydrase IX-expressing cells or tumors also are disclosed.