The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 08, 2020
Filed:
Apr. 09, 2015
Applicant:
Brandeis University, Waltham, MA (US);
Assignee:
BRANDEIS UNIVERSITY, Waltham, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 49/18 (2006.01); G01N 33/543 (2006.01); G01N 33/574 (2006.01); C12Q 1/42 (2006.01); A61K 47/52 (2017.01); A61K 47/69 (2017.01); A61K 47/64 (2017.01); A61K 38/08 (2019.01); A61K 41/00 (2020.01); A61K 45/06 (2006.01); B82Y 5/00 (2011.01); A61B 17/00 (2006.01);
U.S. Cl.
CPC ...
A61K 49/1866 (2013.01); A61K 38/08 (2013.01); A61K 41/0052 (2013.01); A61K 45/06 (2013.01); A61K 47/52 (2017.08); A61K 47/64 (2017.08); A61K 47/6923 (2017.08); A61K 47/6929 (2017.08); C12Q 1/42 (2013.01); G01N 33/54326 (2013.01); G01N 33/574 (2013.01); G01N 33/57492 (2013.01); A61B 2017/00345 (2013.01); B82Y 5/00 (2013.01); G01N 2333/916 (2013.01); G01N 2440/14 (2013.01); G01N 2440/30 (2013.01);
Abstract
The invention relates to an enzymatically responsive product that includes an amino acid residue conjugated to a magnetic particle, wherein the amino acid residue is phosphorylated or sulfated or comprises an ester-moiety linked via peptide bond. Compositions containing the enzymatically responsive product, and the use thereof for separating distinct types of mammalian cells (e.g., cancer cells from normal cells), for treating a cancerous condition, and imaging cancer cells are also disclosed.