The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 08, 2020
Filed:
Mar. 02, 2018
Applicant:
Janssen Biotech, Inc., Horsham, PA (US);
Inventors:
Michael Quigley, Ambler, PA (US);
Andressa Smith, Lansdale, PA (US);
Assignee:
Janssen Biotech, Inc., Horsham, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 31/4439 (2006.01); A61P 35/00 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); A61K 45/06 (2006.01); A61K 31/501 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39558 (2013.01); A61K 31/4439 (2013.01); A61K 31/501 (2013.01); A61K 39/395 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07K 16/2866 (2013.01); C07K 16/2878 (2013.01); C07K 16/3046 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/30 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/75 (2013.01); C07K 2317/76 (2013.01);
Abstract
The present invention is directed to methods for treating cancer, preferably a solid tumor or hematological malignancy, including for example pancreatic cancer, lung cancer (including but not limited to non-small cell lung cancer (NSCLC)), prostate cancer, colorectal cancer, breast cancer, melanoma or non-Hodgkin's lymphoma, comprising administering to a subject in need thereof a therapeutically effective amount of co-therapy comprising, consisting or consisting essentially of (a) a small molecule CSF-1R inhibitor and (b) an agonistic antibody that binds CD40.