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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10857211 B1

PDFFull Text
Date of Patent:
Dec. 08, 2020

Filed:

Nov. 22, 2016

Genomic instability markers in fanconi anemia

Applicant:

Children's Hospital Medical Center, Cincinnati, OH (US);

Inventors:

Susanne I. Wells, Cincinnati, OH (US);

Kenneth D. R. Setchell, Cincinnati, OH (US);

Lindsey Romick-Rosendale, Cincinnati, OH (US);

Wujuan Zhang, Cincinnati, OH (US);

Xueheng Zhao, Cincinnati, OH (US);

Assignee:

CHILDREN'S HOSPITAL MEDICAL CENTER, Cincinnati, OH (US);

Attorney:

Thompson Hine LLP

Primary Examiner:

Kortney L Klinkel

Assistant Examiner:

William Y Lee

Int. Cl.
CPC ...
A61K 38/46 (2006.01); A61K 47/26 (2006.01); C12N 15/113 (2010.01); A61K 31/445 (2006.01); A61K 31/451 (2006.01); C12Q 1/6886 (2018.01); G01N 33/574 (2006.01); G01N 33/92 (2006.01);
U.S. Cl.
CPC ...
A61K 38/465 (2013.01); A61K 31/445 (2013.01); A61K 31/451 (2013.01); A61K 47/26 (2013.01); C12N 15/113 (2013.01); C12Q 1/6886 (2013.01); G01N 33/57426 (2013.01); G01N 33/92 (2013.01); C12N 2310/14 (2013.01); G01N 2800/22 (2013.01);
Abstract

Markers for genomic instability in Fanconi Anemia (FA) and other pathologies for therapeutic and diagnostic uses. In one embodiment, glycosphingolipid metabolism is altered in the FA deficient squamous cell carcinoma (SCC) cells, based on analysis of a metabolomics/lipidomics platform. The data indicated ganglioside metabolism was important in FA patients' susceptibility to SCC progression.

Find Patent Forward Citations

Wells, Susanne. (2020). Genomic instability markers in fanconi anemia (U.S. Patent No. 10857211). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10857211

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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