The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 08, 2020

Filed:

Mar. 15, 2016
Applicant:

Breath Therapeutics Gmbh, Munich, DE;

Inventors:

Martin Knoch, Garmisch-Partenkirchen, DE;

Oliver Denk, Münsing, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/13 (2006.01); A61K 9/127 (2006.01); A61K 9/00 (2006.01); A61K 9/19 (2006.01); A61K 45/06 (2006.01); A61K 47/26 (2006.01);
U.S. Cl.
CPC ...
A61K 38/13 (2013.01); A61K 9/0053 (2013.01); A61K 9/0078 (2013.01); A61K 9/127 (2013.01); A61K 9/19 (2013.01); A61K 45/06 (2013.01); A61K 47/26 (2013.01);
Abstract

The invention relates to cyclosporine formulations for use in the prevention or treatment of pulmonary chronic graft rejection. In particular, the invention provides a cyclosporine liquid formulation for use as an aerosol for inhalation in a method of preventing or treating pulmonarychronic graft rejection in single lung transplanted patients. The formulation is preferably administered once or twice daily. The formulation may be aerosolized with a nebulizer that comprises features for monitoring the time, date and duration of inhalation by the patient, in order to monitor patient adherence. The formulation according to the invention may be combined with standard immunosuppressants and corticosteroids.


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