The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 08, 2020

Filed:

Aug. 13, 2019
Applicant:

Biotheryx, Inc., Chappaqua, NY (US);

Inventors:

Kyle W. H. Chan, San Diego, CA (US);

Paul E. Erdman, San Diego, CA (US);

Leah Fung, San Diego, CA (US);

Frank Mercurio, Rancho Santa Fe, CA (US);

Robert Sullivan, Vista, CA (US);

Assignee:

BioTheryX, Inc., Chappaqua, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/55 (2006.01); A61P 35/02 (2006.01); A61P 35/00 (2006.01); C07D 403/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/55 (2013.01); A61P 35/00 (2018.01); A61P 35/02 (2018.01); C07D 403/04 (2013.01);
Abstract

The present invention provides modulators of protein function, to restore protein homeostasis, including GSPT1 activity. The invention provides methods of modulating protein-mediated diseases, such as GSPT1-mediated diseases, disorders, conditions, or responses. Compositions are also provided. Methods of treatment, amelioration, or prevention of protein-mediated diseases, disorders, and conditions, such as GSPT1-mediated diseases, disorders, and conditions, including cancer and astrogliosis.


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