The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 08, 2020

Filed:

May. 19, 2017
Applicant:

Azure Biotech, Inc., River Vale, NJ (US);

Inventors:

Valerie Ceva, New York, NY (US);

Steven R. Goldstein, New York, NY (US);

Susan L. Levinson, Morris Township, NJ (US);

David D. Thompson, Gales Ferry, CT (US);

Andreas Bernkop-Schnürch, Sankt Veit an der Glan, AT;

Isabelle Nardin, Salzberg, AT;

Assignee:

Azure Biotech, Inc., River Vale, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/40 (2006.01); A61K 9/107 (2006.01); A61K 9/00 (2006.01); A61K 47/10 (2017.01); A61K 47/14 (2017.01); A61K 47/24 (2006.01); A61K 47/26 (2006.01); A61K 47/44 (2017.01);
U.S. Cl.
CPC ...
A61K 31/40 (2013.01); A61K 9/0019 (2013.01); A61K 9/0034 (2013.01); A61K 9/107 (2013.01); A61K 9/1075 (2013.01); A61K 47/10 (2013.01); A61K 47/14 (2013.01); A61K 47/24 (2013.01); A61K 47/26 (2013.01); A61K 47/44 (2013.01);
Abstract

The present disclosure provides pharmaceutical compositions that include one or more selective estrogen receptor modulator(s) (SERM(s), e.g., Lasofoxifene) and four or more pharmaceutically acceptable excipients. The pharmaceutical compositions may be able to form nanodroplets (e.g., by self-nanoemulsifying) in vaginal fluid and to deliver the one or more SERM(s) to the vagina of a female subject. The pharmaceutical compositions may be useful in treating or preventing vulvovaginal atrophy, dyspareunia, sexual dysfunction, osteoporosis, or breast cancer in a female subject.


Find Patent Forward Citations

Loading…