The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2020
Filed:
Apr. 07, 2015
The University Court of the University of Edinburg, Edinburgh Lothian, GB;
Peter Ghazal, Edinburgh Midlothian, GB;
Paul Dickinson, Edinburgh Midlothian, GB;
Thorsten Forster, Edinburgh Midlothian, GB;
Claire Smith, Edinburgh Midlothian, GB;
Ben Stenson, Edinburgh Midlothian, GB;
Mizan Khondoker, Edinburgh Midlothian, GB;
University College Cardiff Consultants Limited, Cardiff, GB;
Abstract
Sepsis remains a leading cause of morbidity and mortality in neonates worldwide. There is also clinically a low threshold for suspicion of infection in neonates, in particular as presentation varies greatly from very subtle to catastrophic collapse. The lack of reliably sensitive tests and the potential life-threatening consequences of delayed treatment of infection results in the widespread use of empirical antibiotics exposing many infants without infection to broad-spectrum antibiotics. The present invention provides a series of patient-invariant biomarkers for screening neonates and other subjects for infection that predicts bacterial infection with high accuracy; and is further shown to have predictive value in identifying infection in suspected cases with blood-culture negative tests.