The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2020
Filed:
May. 08, 2015
Carnegie Mellon University, Pittsburgh, PA (US);
Danith H. Ly, Pittsburgh, PA (US);
Wei-Che Hsieh, Pittsburgh, PA (US);
Iulia Sacui, Owensboro, KY (US);
Arunava Manna, Pittsburgh, PA (US);
Carnegie Mellon University, Pittsburgh, PA (US);
Abstract
A method of making optically pure preparations of chiral γPNA (gamma peptide nucleic acid) monomers is provided. Nano structures comprising chiral γPNA structures also are provided. Methods of amplifying and detecting specific nucleic acids, including in situ methods are provided as well as compositions and kits useful in those methods. Lastly, methods of converting nucleobase sequences from right-handed helical PNA, nucleic acid and nucleic acid analog structures to left-handed γPNA, and vice-versa, are provided.