The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2020
Filed:
May. 12, 2017
Applicant:
Contrafect Corporation, Yonkers, NY (US);
Inventor:
Raymond Schuch, Mountain Lakes, NJ (US);
Assignee:
CONTRAFECT CORPORATION, Yonkers, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/18 (2006.01); C12Q 1/34 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/18 (2013.01); C12Q 1/34 (2013.01); C12Y 302/01017 (2013.01);
Abstract
The present invention provides components, assays and methods for evaluating antibacterial effectiveness and determining minimal inhibitory concentration (MIC) of polypeptides, including lysin polypeptides, that kill bacteria. Modified broth microdilution components and methods are provided, including supplements to enable accurate MIC determination mimicking lysin polypeptide activity in human matrices including serum and blood.