The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 01, 2020

Filed:

Jan. 06, 2016
Applicant:

Pfizer Inc., New York, NY (US);

Inventors:

Fabio Cataldi, Beverly, MA (US);

Robert A. Clare, Wayne, MA (US);

Gail M. Comer, Phoenixville, PA (US);

Vivekananda Pradhan, Acton, MA (US);

Alaa Ahmad, Arlington, MA (US);

Mina Hassan-Zahraee, Cambridge, MA (US);

Mera Krishnan Tilley, Medford, MA (US);

Weidong Zhang, Acton, MA (US);

Anindita Banerjee, Canton, MA (US);

Karen Michelle Page, Merrimack, NH (US);

Michael Steven Vincent, Newton, MA (US);

David J. Von Schack, Arlington, MA (US);

Assignee:

PFIZER INC., New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61P 29/00 (2006.01); A61P 1/04 (2006.01); C12Q 1/6883 (2018.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); A61K 39/39541 (2013.01); A61P 1/04 (2018.01); A61P 29/00 (2018.01); C12Q 1/6883 (2013.01); G01N 33/6893 (2013.01); A61K 2039/505 (2013.01); A61K 2039/545 (2013.01); C07K 2317/565 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); G01N 2800/065 (2013.01); G01N 2800/7095 (2013.01);
Abstract

The present invention provides a method for the treatment of a patient comprising administering to the patient an initial dose of between about 1 mg and about 150 mg of a MAdCAM antagonist antibody. Biomarkers for assessing a patient's response to anti-MAdCAM treatment are also provided.


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