The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 01, 2020

Filed:

Nov. 16, 2017
Applicant:

Eutilex Co., Ltd., Seoul, KR;

Inventor:

Byoung S. Kwon, Seoul, KR;

Assignee:

Eutilex Co., Ltd., Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 14/705 (2006.01); C07K 16/30 (2006.01); C07K 7/06 (2006.01); C07K 14/715 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70578 (2013.01); C07K 7/06 (2013.01); C07K 14/7151 (2013.01); C07K 16/2878 (2013.01); C07K 16/3061 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/34 (2013.01); C07K 2317/55 (2013.01); C07K 2317/74 (2013.01); C07K 2317/75 (2013.01);
Abstract

The present invention relates to a novel epitope to convert T cell to type 17 helper T (T17) cell. Specifically, the present invention relates to an epitope constituting the 41st to 50th amino acids (SEQ ID No.2) of extracellular domain (ECD) of activation-inducible tumor necrosis factor receptor (AITR), an antibody recognizing the epitope, a polynucleotide encoding the epitope, a polynucleotide encoding the antibody, an expression vector comprising the polynucleotide encoding the epitope or antibody, a transformant introduced with the vector, a composition comprising the antibody for converting T cell to T17 cell and a method of conversion for the same, a pharmaceutical composition comprising the antibody for preventing or treating infectious disease, a method for treating infectious disease using the antibody, a composition comprising the antibody for enhancing immunity, and a method for enhancing immunity using the antibody.


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