The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2020
Filed:
Jul. 24, 2018
Bristol-myers Squibb Company, Princeton, NJ (US);
Kirk J. Leister, Fayetteville, NY (US);
Eugene J. Schaefer, Westfield, NJ (US);
Ronald Charles Bates, Irvine, CA (US);
Elizabeth A. Bramhall, Groton, MA (US);
David Michael Didio, Syracuse, NY (US);
Robert Donaldson, Southborough, MA (US);
Alan R. Flesher, Lawrenceville, NJ (US);
Helen Gray Haggerty, Manlius, NY (US);
David Henry Kirkley, East Syracuse, NY (US);
John Malcolm Tabor, Syracuse, NY (US);
Lee K. Tay, Princeton Junction, NJ (US);
Pallaiah Thammana, Manlius, NY (US);
Ajoy Velayudhan, Cary, NC (US);
David Edward Smolin, Pennington, NJ (US);
Reb J. Russell, Doylestown, PA (US);
Thomas James Vanden Boom, Flemington, NJ (US);
Dean Woodrow Brownell, Oswego, NY (US);
Jeffrey Schrimsher, Hillsborough, NC (US);
Joyce Patricia Whitehead, Manlius, NY (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
The invention provides for mammalian cells capable of producing recombinant CTLA4-Ig and variants thereof. The invention also provides for compositions comprising CTLA4-Ig and formulations thereof. The invention further provides for methods for mass-producing CTLA4-Ig from mammalian cells capable of producing this recombinant protein, and for purifying the CTLA4-Ig.