The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2020
Filed:
Aug. 10, 2018
Applicant:
Calithera Biosciences, Inc., South San Francisco, CA (US);
Inventors:
Eric B. Sjogren, Mountain View, CA (US);
Jim Li, San Francisco, CA (US);
Michael Van Zandt, Guilford, CT (US);
Darren Whitehouse, Westbrook, CT (US);
Assignee:
CALITHERA BIOSCIENCES, INC., South San Francisco, CA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07F 5/02 (2006.01); C07K 16/28 (2006.01); A61K 31/69 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07F 5/025 (2013.01); A61K 31/69 (2013.01); A61K 39/3955 (2013.01); A61K 39/39533 (2013.01); A61K 45/06 (2013.01); C07K 16/2818 (2013.01); A61K 2039/507 (2013.01);
Abstract
The invention relates to a novel class of compounds that exhibit activity inhibitory activity toward arginase, and pharmaceutical compositions comprising the compounds of the invention. Also provided herein are methods of treating cancer with the arginase inhibitors of the invention.