The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 01, 2020

Filed:

Dec. 10, 2018
Applicant:

Avexxin As, Trondheim, NO;

Inventors:

Berit Johansen, Oslo, NO;

Marcel Sandberg, Oslo, NO;

Inger-Reidun Aukrust, Oslo, NO;

George Kokotos, Athens, GR;

Johan Evenäs, Lund, SE;

Thomas Brimert, Lund, SE;

Kildahl-Andersen Geir, Oslo, NO;

Assignee:

Avexxin AS, Trondheim, NO;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 513/04 (2006.01); C07D 417/04 (2006.01); C07D 277/56 (2006.01);
U.S. Cl.
CPC ...
C07D 513/04 (2013.01); C07D 277/56 (2013.01); C07D 417/04 (2013.01);
Abstract

A compound of formula (I') wherein Ris H, Calkyl, —(CH)COOH, —(CH)COOCalkyl, —(CH)CONH, —(CH)CONHCalkyl, —(CH)CON(Calkyl), Ris as defined for R; or and Rtaken together with the atoms joining them can form a 6-membered aromatic or non aromatic, saturated or unsaturated, carbocyclic or heteroatom containing (e.g. O, N or S containing) ring optionally substituted by up to 4 groups R; each Ris defined as for Ror is oxo; Ris Calkyl Ar is a Caryl group, wherein the aryl group may be optionally substituted (preferably in the meta or para position relative to O) with one or more Rgroups; each Ris halo, OH, CN, nitro, NH, NHCalkyl, N(Calkyl), haloCalkyl, Caryl group, Carylalkyl, a Calkyl group, C-mono or multiply unsaturated alkenyl group, OCalkyl group, SCalkyl group —OCalkyl-O—Calkyl, —Calkyl-O—Calkyl, —OC-mono or multiply unsaturated alkenyl group, OAr, O(CH)Ar, SAror S(CH)Ar; wherein Aris phenyl, optionally substituted with one or more of halo, trihalomethyl, C-alkoxy, or Calkyl; each q is 1 to 3, preferably 1; each p is 0 to 3; or a salt, ester, solvate, N-oxide, or prodrug thereof.


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