The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2020
Filed:
Jun. 13, 2019
The Scripps Research Institute, La Jolla, CA (US);
Thomas D. Bannister, Palm Beach Gardens, FL (US);
William R. Roush, Jupiter, FL (US);
Jun Yong Choi, Jupiter, FL (US);
Reji Nair, Palm Beach Gardens, FL (US);
Andy S. Tsai, Mystic, CT (US);
Jitendra K. Mishra, Memphis, TN (US);
John L. Cleveland, Land O' Lakes, FL (US);
THE SCRIPPS RESEARCH INSTITUTE, La Jolla, CA (US);
Abstract
The invention provides heterocyclic compounds of formula A, B, and C as described herein that inhibit monocarboxylate transporters, such as MCT1 and MCT4. Compounds of the invention can be used for treatment of a condition in a patient, wherein the condition is characterized by the heightened activity or by the high prevalence of MCT1 and/or MCT4, such as cancer or type II diabetes.