The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2020
Filed:
Apr. 19, 2017
Applicant:
Bristol-myers Squibb Company, Princeton, NJ (US);
Inventors:
Prashantha Gunaga, Bangalore, IN;
Jeremy Richter, Yardley, PA (US);
Navnath Dnyanoba Yadav, Bangalore, IN;
Manoranjan Panda, Bangalore, IN;
Sreenivasulu Godesi, Ardhaveedu Mandal, IN;
Assignee:
Bristol-Myers Squibb Company, Princeton, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); C07D 487/04 (2006.01); C07D 471/04 (2006.01); C07D 271/04 (2006.01); C07D 407/04 (2006.01); C07D 407/06 (2006.01); C07D 413/14 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 271/04 (2013.01); C07D 407/04 (2013.01); C07D 407/06 (2013.01); C07D 413/14 (2013.01); C07D 471/04 (2013.01); C07D 519/00 (2013.01);
Abstract
Disclosed are compounds of Formula (I), or a salt thereof, wherein: X is CRor N; Y is CRor N, provided that Y is N only if X is N; Ris Formulae (A) or (B); each W is independently NRor O; Z is a bond or CHR; and R, R, R, R, L, R, R, R, and n are defined herein. Also disclosed are methods of using such compounds as inhibitors of ROMK, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating cardiovascular diseases.