The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2020
Filed:
Jan. 22, 2020
Applicant:
Theravance Biopharma R&d Ip, Llc, South San Francisco, CA (US);
Inventors:
Robert Murray McKinnell, South San Francisco, CA (US);
Erik Fenster, South San Francisco, CA (US);
Tom M. Lam, South San Francisco, CA (US);
Anthony Francesco Palermo, South San Francisco, CA (US);
Assignee:
Theravance Biopharma R&D IP, LLC, South San Francisco, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 487/04 (2006.01); A61K 9/00 (2006.01); C07D 487/08 (2006.01); A61P 1/00 (2006.01); C07D 471/08 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 9/0014 (2013.01); A61P 1/00 (2018.01); C07D 471/08 (2013.01); C07D 487/04 (2013.01); C07D 487/08 (2013.01);
Abstract
The invention provides compounds of formula (I): or a pharmaceutically-acceptable salt thereof, wherein the variables are defined in the specification, that are inhibitors of JAK kinases, particularly JAK3. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using such compounds to treat gastrointestinal and other inflammatory diseases.