The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 01, 2020

Filed:

Jun. 29, 2017
Applicant:

Calygene Biotechnology, Inc., Camden, DE (US);

Inventor:

Congxin Liang, Palm Beach Gardens, FL (US);

Assignee:

Lysoway Therapeutics, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/04 (2006.01); C07D 401/04 (2006.01); C07D 241/04 (2006.01); C07D 295/096 (2006.01); C07D 213/76 (2006.01); C07D 295/135 (2006.01); C07D 239/48 (2006.01); A61P 21/00 (2006.01); A61P 17/00 (2006.01); A61P 25/16 (2006.01); A61P 25/28 (2006.01);
U.S. Cl.
CPC ...
C07D 403/04 (2013.01); A61P 17/00 (2018.01); A61P 21/00 (2018.01); A61P 25/16 (2018.01); A61P 25/28 (2018.01); C07D 213/76 (2013.01); C07D 239/48 (2013.01); C07D 241/04 (2013.01); C07D 295/096 (2013.01); C07D 295/135 (2013.01); C07D 401/04 (2013.01);
Abstract

The new piperazine derivatives are modulators of TRPML and are useful in treating disorders related to TRPML activities such as lysosome storage diseases, muscular dystrophy, age-related common neurodegenerative diseases, oxidative stress or reactive oxygen species (ROS) related diseases, and ageing.


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