The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2020
Filed:
Oct. 16, 2018
Applicant:
Sumitomo Dainippon Pharma Oncology, Inc., Cambridge, MA (US);
Inventors:
Zhiwei Jiang, Stow, MA (US);
Chiang Jia Li, Cambridge, MA (US);
Wei Li, Wayland, MA (US);
David Leggett, Milton, MA (US);
Assignee:
Sumitomo Dainippon Pharma Oncology, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 333/74 (2006.01); A61K 31/343 (2006.01); C07D 307/92 (2006.01); A61K 31/38 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 307/92 (2013.01); A61K 31/343 (2013.01); A61K 31/38 (2013.01); A61P 35/00 (2018.01); C07D 333/74 (2013.01); Y02A 50/465 (2018.01);
Abstract
The present invention relates to a novel naphtho class of compounds as Stat3 pathway inhibitors and as cancer stem cell inhibitors; to methods of using such compounds to treat cancer; to methods of using such compounds to treat disorders in a mammal related to aberrent Stat3 pathway activity; to pharmaceutical compositions containing such compounds.