The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 01, 2020

Filed:

Sep. 22, 2017
Applicant:

Eisai R&d Management Co., Ltd., Tokyo, JP;

Inventors:

Mark Bock, Boston, MA (US);

Ming-Hong Hao, Quincy, MA (US);

Manav Korpal, Winchester, MA (US);

Vijay Kumar Nyavanandi, Andhra Pradesh, IN;

Xiaoling Puyang, Cambridge, MA (US);

Susanta Samajdar, Kamataka, IN;

Peter Gerard Smith, Arlington, MA (US);

John Wang, Andover, MA (US);

Guo Zhu Zheng, Lexington, MA (US);

Ping Zhu, Boxborough, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/00 (2006.01); A01N 43/46 (2006.01); A61K 31/55 (2006.01); C07D 231/56 (2006.01); C07D 403/12 (2006.01); C07D 471/14 (2006.01); C07D 403/06 (2006.01); C07D 401/06 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07D 231/56 (2013.01); C07D 401/06 (2013.01); C07D 401/14 (2013.01); C07D 403/06 (2013.01); C07D 403/12 (2013.01); C07D 471/14 (2013.01);
Abstract

Disclosed herein are compounds, or pharmaceutically acceptable salts thereof, and methods of using the compounds for treating breast cancer by administration to a subject in need thereof a therapeutically effective amount of the compounds or pharmaceutically acceptable salts thereof. The breast cancer may be an ER-positive breast cancer and/or the subject in need of treatment may express a mutant ER-α protein.


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