The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 01, 2020

Filed:

Feb. 26, 2018
Applicant:

Visugen Global Llc, Aurora, CO (US);

Inventors:

John C. Gerdes, Littleton, CO (US);

Kirsten L. Nelson, Castle Pines, CO (US);

Kris Buchanan, Fort Collins, CO (US);

Assignee:

VISUGEN GLOBAL LLC, Aurora, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); B01D 15/22 (2006.01); B01J 20/08 (2006.01); G01N 15/06 (2006.01); G01N 33/00 (2006.01); G01N 33/48 (2006.01); G01N 15/10 (2006.01); B01J 20/28 (2006.01); G01N 33/543 (2006.01); G01N 35/00 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502715 (2013.01); B01D 15/22 (2013.01); B01J 20/08 (2013.01); B01J 20/28028 (2013.01); B01L 3/502761 (2013.01); G01N 15/10 (2013.01); G01N 33/54366 (2013.01); G01N 35/00069 (2013.01); G01N 35/00871 (2013.01); B01J 2220/42 (2013.01); B01L 2200/02 (2013.01); B01L 2200/0647 (2013.01); B01L 2300/069 (2013.01); B01L 2300/0654 (2013.01); B01L 2400/086 (2013.01); G01N 2035/00158 (2013.01); G01N 2035/00881 (2013.01);
Abstract

Systems and methods that enable the rapid identification of target molecules present in a sample at low concentrations is provided. The system includes a sample volume, and a detection structure that is connected to the sample volume by a conduit. The detection structure includes a microfluidic chip that defines a plurality of fluid channels. The walls of the fluid channels are formed from or covered with a metal oxide to which target molecules attach. After the sample volume has been passed through the detection structure, and in particular through the channels, visible microparticles are passed through the detection structure. The visible microparticles are configured to have an affinity for the target molecules. The microfluidic chip is then imaged to detect visible microparticles, and to thereby obtain information regarding the presence of the target molecules.


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