The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2020
Filed:
Sep. 07, 2018
Applicant:
Industry-university Cooperation Foundation Hanyang University, Seoul, KR;
Inventors:
Chae Ok Yun, Seoul, KR;
A-Rum Yoon, Gyeonggi-do, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/69 (2017.01); A61K 48/00 (2006.01); A61K 47/50 (2017.01); A61K 39/395 (2006.01); A61K 47/32 (2006.01); A61K 47/60 (2017.01); A61K 47/68 (2017.01); A61K 47/59 (2017.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6901 (2017.08); A61K 39/395 (2013.01); A61K 47/32 (2013.01); A61K 47/50 (2017.08); A61K 47/595 (2017.08); A61K 47/60 (2017.08); A61K 47/6849 (2017.08); A61K 48/00 (2013.01); A61P 35/00 (2018.01);
Abstract
The present invention relates to a complex of an antitumor adenovirus coated with ErbB-PEG-PAMAM and the use thereof. When using the complex of the present invention, a tumor cell-specific gene transfer effect by an excellent tumor cell infiltration ability is excellent, hepatotoxicity is low, a blood flow retention time is prolonged. Thus, the complex of the present invention can be used as a pharmaceutical composition for the treatment of a tumor and a gene therapy agent which can be administered systemically.