The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2020
Filed:
May. 19, 2016
Applicant:
Yeda Research and Development Co. Ltd., Rehovot, IL;
Inventors:
Valery Krizhanovsky, Rehovot, IL;
Yossi Ovadya, Rehovot, IL;
Assignee:
YEDA RESEARCH AND DEVELOPMENT CO. LTD., Rehovot, IL;
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/68 (2017.01); A61P 35/00 (2006.01); A61K 45/06 (2006.01); C07K 16/18 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 47/6843 (2017.08); A61K 45/06 (2013.01); A61K 47/6807 (2017.08); A61K 47/6849 (2017.08); A61P 35/00 (2018.01); C07K 16/18 (2013.01); C12N 15/1137 (2013.01); C12N 2310/14 (2013.01); C12N 2310/3513 (2013.01);
Abstract
A method of targeting a pharmaceutical agent to a senescent cell is disclosed. The method comprises administering the pharmaceutical agent to the subject, wherein said pharmaceutical agent is attached to an affinity moiety, said affinity moiety being capable of binding specifically to a polypeptide selected from the group consisting of HSP90B1, DNAJB4, PI4K2A, DBN1, PRKCSH, SPTBN1, NPM1, ITGA3 and a polypeptide set forth in Table 1. The targeting may be for therapeutics or diagnostics.