The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 2020
Filed:
Feb. 02, 2012
Joseph E. Blaney, Gettysburg, PA (US);
Jason Paragas, Bethesda, MD (US);
Peter Jahrling, Gaithersburg, MD (US);
Reed Johnson, Frederick, MD (US);
Matthias Schnell, Harleysville, PA (US);
Joseph E. Blaney, Gettysburg, PA (US);
Jason Paragas, Bethesda, MD (US);
Peter Jahrling, Gaithersburg, MD (US);
Reed Johnson, Frederick, MD (US);
Matthias Schnell, Harleysville, PA (US);
Thomas Jefferson University, Philadelphia, PA (US);
The United States of America, as Represented by the Secretary, Department of Health and Human Services Services, Bethesda, MD (US);
Abstract
The present invention provides methods and compositions for inducing an immune response that confers dual protection against infections by either or both of a rabies virus and a filovirus, and/or which can be used therapeutically for an existing infection with rabies virus and/or a filovirus to treat at least one symptom thereof and/or to neutralize or clear the infecting agents. In particular, the present invention provides a recombinant rabies virus vector comprising a nucleotide sequence encoding at least one filovirus glycoprotein or an immunogenic fragment thereof, as well as pharmaceutical compositions comprising the vaccine vectors.