The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 01, 2020

Filed:

Jul. 25, 2016
Applicant:

Novan, Inc., Morrisville, NC (US);

Inventors:

Kimberly McHale, Hillsborough, NC (US);

Nathan Stasko, Chapel Hill, NC (US);

Assignee:

Novan, Inc., Morrisville, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/137 (2006.01); A61K 31/655 (2006.01); A61K 31/695 (2006.01); A61P 31/10 (2006.01); A61K 41/00 (2020.01); C01B 21/24 (2006.01); A61K 45/06 (2006.01); A61K 31/795 (2006.01); A61K 31/80 (2006.01); A61K 33/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/137 (2013.01); A61K 31/655 (2013.01); A61K 31/695 (2013.01); A61K 31/795 (2013.01); A61K 31/80 (2013.01); A61K 33/00 (2013.01); A61K 41/0042 (2013.01); A61K 45/06 (2013.01); A61P 31/10 (2018.01); C01B 21/24 (2013.01);
Abstract

Provided are combinations comprising terbinafine or a pharmaceutically acceptable salt thereof and a NO source. The combination may be a synergistic combination. Also provided are methods of treating and/or preventing a fungal infection in a subject comprising administering terbinafine or a pharmaceutically acceptable salt thereof to the subject; and administering a NO source to the subject, thereby treating and/or preventing the fungal infection in the subject. The dose of terbinafine or a pharmaceutically acceptable salt thereof and the dose of the NO source administered to the subject may achieve a synergistic effect.


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