The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 24, 2020
Filed:
Jul. 21, 2017
Applicants:
Antara Datta, Piscataway, NJ (US);
Jason Trama, Burlington, NJ (US);
Inventors:
Antara Datta, Piscataway, NJ (US);
Jason Trama, Burlington, NJ (US);
Assignee:
Medical Diagnostic Laboratories, LLC, Hamilton, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/569 (2006.01); G01N 33/574 (2006.01); C07K 16/18 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57407 (2013.01); C07K 16/18 (2013.01); G01N 33/574 (2013.01); G01N 2333/82 (2013.01);
Abstract
The present invention is directed to a method of detecting a DEK protein in a human urine sample using an ELISA assay. Methods and compositions for detection of DEK using mAb 260-6F9F6 (as detection antibody) and mAb 16-2C9C3 (as capture antibody) in human urine are provided herein. Specifically, the ELISA assay utilizes a capture mAb and a detection mAb to yield a high sensitivity of <50 ng/mL. The presence of DEK in urine is useful in predicting or diagnosing the occurrence of bladder cancer in humans.