The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 24, 2020
Filed:
Jun. 01, 2016
Applicant:
Biogen MA Inc., Cambridge, MA (US);
Inventors:
Assignee:
Biogen MA Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C12P 21/00 (2006.01); C12N 5/00 (2006.01); C07K 16/28 (2006.01); C12N 5/073 (2010.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
C12P 21/005 (2013.01); C07K 16/2842 (2013.01); C12N 5/0018 (2013.01); C12N 5/0603 (2013.01); C12N 5/0682 (2013.01); C07K 2317/14 (2013.01); C07K 2317/41 (2013.01); C12N 2500/20 (2013.01); C12N 2511/00 (2013.01);
Abstract
The present invention pertains to a cell culture medium comprising manganese as a media supplement, which was shown to control recombinant protein glycosylation and methods of using thereof. The present invention further pertains to a method of controlling or manipulating glycosylation of a recombinant protein of interest in a large scale cell culture.