The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 24, 2020
Filed:
Nov. 14, 2014
Applicant:
Zhejiang Hisun Pharmaceutical Co., Ltd, Zhejiang, CN;
Inventors:
Jun Huang, Zhejiang, CN;
Zhen Yu, Zhejiang, CN;
Meihong Li, Zhejiang, CN;
Linghui Zheng, Zhejiang, CN;
Na Li, Zhejiang, CN;
Haibin Wang, Zhejiang, CN;
Hua Bai, Zhejiang, CN;
Assignee:
Zhejiang Hisun Pharmaceutical Co., LTD., Zhejiang, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); C12P 19/62 (2006.01); C12N 15/74 (2006.01);
U.S. Cl.
CPC ...
C12P 19/62 (2013.01); C12N 15/74 (2013.01);
Abstract
The invention provides a construction method of spinosad heterologous expression strain, a spinosad heterologous expression strain obtained by the method and use thereof in preparing spinosad. The method utilizes a plurality of homologous recombination to replace the erythromycin synthetic gene cluster ofwith the spinosad synthetic gene cluster and the rhamnose synthetic gene cluster, such that theproduces spinosad.