The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 24, 2020

Filed:

Jun. 03, 2016
Applicants:

Ibio, Inc., New York, NY (US);

Novici Biotech Llc, Vacaville, CA (US);

Musc Foundation for Research Development, Charleston, SC (US);

Inventors:

Carol Feghali-Bostwick, Mt Pleasant, SC (US);

Terence E Ryan, Eagleville, PA (US);

Hal S. Padgett, Vacaville, CA (US);

Matthew McGee, Vacaville, CA (US);

Assignees:

iBio, Inc., New York, NY (US);

MUSC FOUNDATION FOR RESEARCH DEVELOPMENT, Charleston, NC (US);

NOVICI BIOTECH LLC, Vacaville, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/82 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8257 (2013.01); C07K 2319/036 (2013.01); C07K 2319/30 (2013.01);
Abstract

This document provides materials and methods for producing endostatin fusion polypeptides having anti-fibrotic activity. For example, provided herein are fusion polypeptides having an IgG Fc domain and a portion of human endostatin that can form high molecular weight multimers, as well as methods for producing such fusion polypeptides in plant cells.


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