The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 24, 2020
Filed:
Jan. 09, 2018
Ganymed Pharmaceuticals Ag, Mainz, DE;
Johannes Gutenberg-universitat Mainz, Mainz, DE;
Ugur Sahin, Mainz, DE;
Ozlem Tureci, Mainz, DE;
Michael Koslowski, Oberschleissheim, DE;
Korden Walter, Wiesbaden, DE;
Maria Kreuzberg, Mainz, DE;
Sylvia Luxen, Mannheim, DE;
Ganymed Pharmaceuticals GmbH, Mainz, DE;
Johannes Gutenberg-Universitat Mainz, Mainz, DE;
Abstract
The invention relates to the treatment and/or prevention of tumor diseases associated with cells expressing CLDN6, in particular cancer and cancer metastasis using antibodies which bind to CLDN6. The present application demonstrates that the binding of antibodies to CLDN6 on the surface of tumor cells is sufficient to inhibit growth of the tumor and to prolong survival and extend the lifespan of tumor patients. Furthermore, binding of antibodies to CLDN6 is efficient in inhibiting growth of CLDN6 positive germ cell tumors such as teratocarcinomas or embryonal carcinomas, in particular germ cell tumors of the testis.