The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 24, 2020
Filed:
Sep. 17, 2014
Applicant:
Children's Medical Center Corporation, Boston, MA (US);
Inventors:
Florian E. Winau, Boston, MA (US);
Ji Hyung Kim, Brookline, MA (US);
Assignee:
CHILDREN'S MEDICAL CENTER CORPORATION, Boston, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 16/28 (2006.01); A61K 31/713 (2006.01); A61K 31/05 (2006.01); G01N 33/50 (2006.01); A61K 9/00 (2006.01); A61K 31/04 (2006.01); A61K 31/437 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); A61K 9/0014 (2013.01); A61K 9/0019 (2013.01); A61K 31/04 (2013.01); A61K 31/05 (2013.01); A61K 31/437 (2013.01); A61K 31/713 (2013.01); A61K 39/3955 (2013.01); G01N 33/5044 (2013.01); G01N 33/5047 (2013.01); A61K 2039/505 (2013.01); C07K 2317/76 (2013.01); G01N 2333/70539 (2013.01); G01N 2800/202 (2013.01);
Abstract
The methods, compositions, and assays described herein are based, in part, on the discovery that CD1a mediates inflammation related to certain conditions such as urushiol exposure, psoriasis and other inflammatory skin diseases. One aspect provided herein relates to a method for treating or preventing an inflammatory skin disease, the method comprising: administering a therapeutically effective amount of an inhibitor of CD 1a to a subject having an inflammatory skin disease, thereby treating or preventing the inflammatory skin diseases.