The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 24, 2020

Filed:

Oct. 30, 2014
Applicant:

Japan Science and Technology Agency, Kawaguchi, JP;

Inventors:

Kenzo Fujimoto, Nomi, JP;

Shigetaka Nakamura, Nomi, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/06 (2006.01); C07H 19/04 (2006.01); C07H 21/04 (2006.01); C07H 19/073 (2006.01); C07H 19/10 (2006.01); C07H 19/044 (2006.01);
U.S. Cl.
CPC ...
C07H 19/06 (2013.01); C07H 19/04 (2013.01); C07H 19/044 (2013.01); C07H 19/073 (2013.01); C07H 19/10 (2013.01); C07H 21/04 (2013.01); C12Q 2525/101 (2013.01); C12Q 2525/117 (2013.01);
Abstract

Provided is a means for preventing the inactivation of a photoresponsive nucleic acid probe by suppressing the formation of a photocrosslink between a modified nucleotide having a structure corresponding to the monomer of Formula (II) or an amino acid analogue of a nucleotide having a structure corresponding to the monomer of Formula (III) and a modified nucleotide having a structure corresponding to the monomer of Formula (I), wherein the modified nucleotide replaces at least one constituent nucleotide which is the photocrosslinkable 1-thyminyl or 1-uracilyl, by substituting at least one constituent nucleotide which is the photocrosslinkable 1-thyminyl or 1-uracilyl with a modified nucleotide having a structure corresponding to the monomer of Formula (I).


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