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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10844045 B1

PDFFull Text
Date of Patent:
Nov. 24, 2020

Filed:

Jun. 16, 2017

Pharmaceutical salts n-(2-(2-(dimethylamino)ethoxy)-4-methoxy-5-((4-(1-methyl-1h-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide and crystalline forms thereof

Applicant:

Beta Pharma, Inc., Wilmington, DE (US);

Inventors:

Michael N. Greco, Lansdale, PA (US);

Michael J. Costanzo, Warminster, PA (US);

Michael A. Green, Easton, PA (US);

Jirong Peng, Mequon, WI (US);

Victoria Lynn Wilde, Montclair, NJ (US);

Don Zhang, Princeton, NJ (US);

Assignee:

BETA PHARMA, INC., Wilmington, DE (US);

Attorney:

Fox Rothschild LLP

Primary Examiner:

Paul V Ward

Int. Cl.
CPC ...
C07D 403/04 (2006.01); C07C 309/04 (2006.01); C07C 309/30 (2006.01); A61P 35/04 (2006.01); A61P 35/00 (2006.01); A61K 31/506 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 403/04 (2013.01); A61K 31/506 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); A61P 35/04 (2018.01); C07C 309/04 (2013.01); C07C 309/30 (2013.01); C07B 2200/13 (2013.01);
Abstract

Crystalline forms of N-(2-(2-(dimethylamino)ethoxy)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide (1) and its pharmaceutically acceptable salts and compositions thereof useful for the treatment or prevention of diseases or medical conditions mediated through mutated forms of epidermal growth factor receptor (EGFR), such as various cancers, are disclosed.

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Greco, Michael. (2020). Pharmaceutical salts n-(2-(2-(dimethylamino)ethoxy)-4-methoxy-5-((4-(1-methyl-1h-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide and crystalline forms thereof (U.S. Patent No. 10844045). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10844045

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