The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 24, 2020
Filed:
Jun. 14, 2019
Applicant:
Vanderbilt University, Nashville, TN (US);
Inventors:
Joseph R. Alvarado, Nashville, TN (US);
Shaun R. Stauffer, Brentwood, TN (US);
Rocco D. Gogliotti, Kingston Springs, TN (US);
Changho Han, Nashville, TN (US);
Kenneth M. Meyers, Nashville, TN (US);
Jianhua Tian, Nashville, TN (US);
Jonathan D. Macdonald, Nashville, TN (US);
Stephen W. Fesik, Nashville, TN (US);
Taekyu Lee, Brentwood, TN (US);
Assignee:
Vanderbilt University, Nashville, TN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/10 (2006.01); A61P 35/00 (2006.01); C07D 401/14 (2006.01); C07D 401/06 (2006.01); C07D 405/10 (2006.01); C07D 233/88 (2006.01); C07D 403/10 (2006.01); C07D 417/12 (2006.01); C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
C07D 401/10 (2013.01); A61P 35/00 (2018.01); C07D 233/88 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/10 (2013.01); C07D 405/10 (2013.01); C07D 417/12 (2013.01);
Abstract
Described are imino-azacycle-benzamide compounds that inhibit WDR5 and associated protein-protein interactions, pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for treating disorders and conditions in a subject.