The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 24, 2020

Filed:

Nov. 04, 2016
Applicant:

Robert Bosch Gmbh, Stuttgart, DE;

Inventors:

Nadezda Fomina, Redwood City, CA (US);

Christopher Johnson, San Carlos, CA (US);

Habib Ahmad, Sunnyvale, CA (US);

Christoph Lang, Cupertino, CA (US);

Franz Laermer, Weil der Stadt, DE;

Assignee:

ROBERT BOSCH GMBH, Stuttgart, DE;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/6825 (2018.01); B01L 3/00 (2006.01); C12N 15/10 (2006.01); G01N 27/327 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502715 (2013.01); B01L 3/5027 (2013.01); C12N 15/1003 (2013.01); C12Q 1/6825 (2013.01); B01L 2300/087 (2013.01); B01L 2400/046 (2013.01); C12Q 2527/119 (2013.01); C12Q 2565/607 (2013.01); G01N 27/3277 (2013.01);
Abstract

At least one electrode is integrated on a lab on a chip cartridge in a sample preparation chamber of the cartridge, a DNA hybridization chamber of the cartridge, a protein assay chamber of the cartridge, and/or a detection chamber of the cartridge, for example, where the electrode is used to generate pH electrochemically in order to activate, deactivate, or intermediately attenuate an enzyme's activity on demand, in order to increase the fidelity of analyte detection, for cell lysis, for protein extraction, for DNA dehybridization, for primer hybridization control, for sample pre concentration, and/or for washing to remove non target species.


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