The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 24, 2020

Filed:

Dec. 19, 2016
Applicant:

The Johns Hopkins University, Baltimore, MD (US);

Inventors:

Xiomara Calderon-Colon, Laurel, MD (US);

George L. Coles, Jr., Baltimore, MD (US);

Assignee:

The Johns Hopkins University, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/22 (2006.01);
U.S. Cl.
CPC ...
A61K 49/223 (2013.01);
Abstract

Example substances and methods relating to contrast agents are provided. An example method includes combining a surface active protein, a stabilizer, and a dispersion media to form a solution. The example method may further include aerating the solution in a gas to form a contrast agent comprising at least one microbubble formed from an interaction between the surface active protein and the stabilizer. A diameter of the at least one microbubble may be proportional to a pressure of an external environment of the contrast agent, such that measurement of the diameter may allow for measurement of the pressure.


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