The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 24, 2020

Filed:

Aug. 20, 2018
Applicant:

Virginia Commonwealth University, Richmond, VA (US);

Inventor:

Jason Carlyon, Richmond, VA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); A61K 39/00 (2006.01); A61K 31/7088 (2006.01); G01N 33/569 (2006.01); C07K 14/29 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0233 (2013.01); A61K 31/7088 (2013.01); C07K 14/29 (2013.01); G01N 33/56911 (2013.01); A61K 2039/70 (2013.01); C07K 2319/00 (2013.01); C07K 2319/03 (2013.01); C07K 2319/21 (2013.01); C07K 2319/23 (2013.01); C07K 2319/40 (2013.01); C07K 2319/70 (2013.01); G01N 2333/195 (2013.01); Y02A 50/403 (2018.01);
Abstract

surface protein AipA and/or fragments thereof which comprise an invasin domain are used in compositions suitable to elicit an immune response to treat or prevent infections caused by tick-born bacteria of the Anaplasmatacaea family. AipA proteins and protein fragments or antibodies directed to AipA proteins and protein fragments are also used in diagnostic assays to detect exposure to and/or infection with Anaplasmatacaea. AipA and/or fragments thereof are also used for these purposes in combination with one or both of Asp14 and OmpA proteins and/or fragments thereof which comprise an invasin domain. Homologs of these proteins are also used in the compositions and assays.


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