The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 24, 2020
Filed:
Sep. 29, 2016
Applicants:
Centre National DE LA Recherche Scientifique, Paris, FR;
Ecole Normale Superieure, Paris, FR;
Inventors:
Alain Prochiantz, Paris, FR;
Ariel Di Nardo, Palaiseau, FR;
Marine Beurdeley, Paris, FR;
Takao Hensch, Newton, MA (US);
Assignees:
Centre National de la Recherche Scientifique, Paris, FR;
Ecole Normale Superieure, Paris, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/18 (2006.01); A61K 49/00 (2006.01); A61B 5/00 (2006.01); C07K 14/475 (2006.01); C07K 14/48 (2006.01); C07K 14/00 (2006.01); A61K 38/46 (2006.01); C07K 14/47 (2006.01); A61K 47/62 (2017.01); A61K 38/17 (2006.01); C12N 9/16 (2006.01); A61L 27/38 (2006.01); C12N 5/079 (2010.01); C12N 15/85 (2006.01); C12N 5/0793 (2010.01); A61P 27/02 (2006.01); A61P 25/28 (2006.01); C12Q 1/6881 (2018.01); A61P 25/00 (2006.01); A61L 27/36 (2006.01); A61P 43/00 (2006.01); C12N 15/90 (2006.01); C12N 5/16 (2006.01); C12N 5/071 (2010.01); G01N 33/50 (2006.01); A61K 35/30 (2015.01); G01N 33/574 (2006.01); A61K 9/00 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
A61K 38/465 (2013.01); A61K 38/1709 (2013.01); A61K 47/62 (2017.08); C07K 14/47 (2013.01); C07K 14/4702 (2013.01); C12N 9/16 (2013.01); C12Y 301/03001 (2013.01); A61K 9/0048 (2013.01); A61K 35/12 (2013.01); A61K 35/30 (2013.01); A61L 27/3604 (2013.01); A61L 27/383 (2013.01); A61L 2300/252 (2013.01); A61L 2300/64 (2013.01); A61P 25/00 (2018.01); A61P 25/28 (2018.01); A61P 27/02 (2018.01); A61P 43/00 (2018.01); C07K 2319/00 (2013.01); C07K 2319/03 (2013.01); C07K 2319/33 (2013.01); C12N 5/0602 (2013.01); C12N 5/0618 (2013.01); C12N 5/0619 (2013.01); C12N 5/0621 (2013.01); C12N 5/16 (2013.01); C12N 15/85 (2013.01); C12N 15/907 (2013.01); C12N 2501/40 (2013.01); C12N 2501/50 (2013.01); C12N 2501/58 (2013.01); C12N 2502/085 (2013.01); C12N 2506/08 (2013.01); C12N 2830/008 (2013.01); C12Q 1/6881 (2013.01); G01N 33/5005 (2013.01); G01N 33/5044 (2013.01); G01N 33/5058 (2013.01); G01N 33/57496 (2013.01); G01N 2500/10 (2013.01); G01N 2800/164 (2013.01); G01N 2800/168 (2013.01);
Abstract
The disclosure provides a method of delivering a polypeptide molecule to an Otx2 target cell, including contacting the target cell with a chimeric polypeptide having (i) a targeting peptide consisting of SEQ ID NO: 2 and (ii) the polypeptide molecule.