The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 24, 2020
Filed:
Mar. 21, 2019
Applicants:
Mta Támogatott Kutatócsoportok Irodája, Budapest, HU;
Semmelweis Egyetem, Budapest, HU;
Sigmadrugs Kft., Budapest, HU;
Inventors:
Assignees:
Támogatott Kutatócsoportok Irodája, Budapest, HU;
Semmelweis Egyetem, Budapest, HU;
SigmaDrugs Kft., Budapest, HU;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/5375 (2006.01); A61K 31/4985 (2006.01); A61K 31/495 (2006.01); A61K 31/4515 (2006.01); A61K 31/4468 (2006.01); A61K 31/4453 (2006.01); A61K 31/135 (2006.01); A61K 31/341 (2006.01); A61K 31/215 (2006.01); A61K 31/15 (2006.01); A61K 31/138 (2006.01); A61K 31/402 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5375 (2013.01); A61K 31/135 (2013.01); A61K 31/138 (2013.01); A61K 31/15 (2013.01); A61K 31/215 (2013.01); A61K 31/341 (2013.01); A61K 31/402 (2013.01); A61K 31/4453 (2013.01); A61K 31/4468 (2013.01); A61K 31/4515 (2013.01); A61K 31/495 (2013.01); A61K 31/4985 (2013.01);
Abstract
Compositions and methods for the prevention, inhibition, and/or treatment of progressive fibrosis present in various fibroproliferative disorders. Embodiments relate to the use of Sigma-1 receptor agonists for use in the treatment of prevention of progressive fibrosis characterized by the over proliferation of ECM producing cells, e.g. myofibroblasts and by the excessive deposition of ECM components in a medical or disease condition. Preferred Sigma-1 agonists are disclosed.