The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 17, 2020

Filed:

Sep. 27, 2018
Applicant:

The Johns Hopkins University, Baltimore, MD (US);

Inventors:

Avindra Nath, Ellicott City, MD (US);

Tongguang Wang, Lutherville, MD (US);

Christina Michelle Morris-Berry, Baltimore, MD (US);

Harvey Singer, Baltimore, MD (US);

Assignee:

The Johns Hopkins University, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/566 (2006.01); A61K 38/00 (2006.01); C12Q 1/68 (2018.01); G01N 33/68 (2006.01); A61K 31/4184 (2006.01); A61K 31/4525 (2006.01); A61K 39/395 (2006.01); A61K 31/7105 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6854 (2013.01); A61K 31/4184 (2013.01); A61K 31/4525 (2013.01); A61K 31/7105 (2013.01); A61K 39/3955 (2013.01); G01N 33/6893 (2013.01); C07K 16/2869 (2013.01); C07K 2317/10 (2013.01); C07K 2317/21 (2013.01); C07K 2317/73 (2013.01); C07K 2317/75 (2013.01); G01N 2333/705 (2013.01); G01N 2333/726 (2013.01); G01N 2800/30 (2013.01); G01N 2800/50 (2013.01);
Abstract

The present invention relates to the field of autism. More specifically, the present invention provides methods for treating individuals with autism spectrum disorders. The present invention also provides methods for predicting a likelihood of ASD. In one embodiment, a method for treating a female patient having a high risk factor of having children with ASD comprises the steps of (a) identifying in a sample taken from the female patient the presence of AT-1 antibodies; and (b) administering an effective amount of an AT-1 inhibitor or inhibitor of AT-1 antibodies to the female patient.


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