The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 17, 2020
Filed:
Aug. 23, 2018
The Regents of the University of California, Oakland, CA (US);
Compliance Decisions, Inc., Irvine, CA (US);
Yu-Hwa Lo, San Diego, CA (US);
Wen Qiao, Suzhou, CN;
Tiantian Zhang, San Diego, CA (US);
Ian Lian, Alhambra, CA (US);
Tony Minghung Yen, Santa Clara, CA (US);
The Regents of the University of California, Oakland, CA (US);
Compliance Decisions, Inc., Irvine, CA (US);
Abstract
Methods, systems, and devices are disclosed for enrichment and detection of molecules of a target biomarker. In one aspect, In one aspect, a biosensor device for enriching and detecting biomarker molecules include a substrate, and a microarray of hydrophilic islands disposed on the substrate. A sensing area on each of the microarray hydrophilic islands is structured to anchor bio-molecular probes of at least one type for detecting molecules of a target biomarker and to attract an array of nanodroplets of a biomarker solution that includes the target biomarker molecules. A hydrophobic surface is disposed to surround the microarray of hydrophilic islands.