The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 17, 2020
Filed:
Feb. 29, 2016
Applicant:
Cellectis, Paris, FR;
Inventors:
Thomas Stoddard, St. Louis Park, MN (US);
Song Luo, Chicago, IL (US);
Assignee:
CELLECTIS, Paris, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/82 (2006.01); A01H 4/00 (2006.01); C12N 9/22 (2006.01); C12N 15/52 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8213 (2013.01); A01H 4/008 (2013.01); C12N 9/22 (2013.01); C12N 15/52 (2013.01); C12N 15/8241 (2013.01); C12Y 301/00 (2013.01); C12N 2840/10 (2013.01);
Abstract
Materials and methods for genome engineering through transient expression of a targeted nuclease are described herein. For example, the methods described herein can include introducing into a cell a messenger RNA (mRNA) that encodes a nuclease targeted to a selected sequence within the cell, where the stability of the mRNA is modified by the addition of untranslated regions (UTRs).