The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 17, 2020
Filed:
Aug. 20, 2015
Applicant:
Akesion Gmbh, Schriesheim, DE;
Inventors:
Klaus Rübsamen, Neustadt, DE;
Stephan Witte, Schriesheim, DE;
Assignee:
Akesion GmbH, Schriesheim, DE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/64 (2006.01); A61K 38/48 (2006.01); C07K 19/00 (2006.01); C07K 16/46 (2006.01); A61L 31/04 (2006.01); C07K 14/765 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/6424 (2013.01); A61K 38/482 (2013.01); A61L 31/047 (2013.01); C07K 14/765 (2013.01); C12Y 304/21074 (2013.01); A61K 38/00 (2013.01); C07K 2319/30 (2013.01); C07K 2319/31 (2013.01);
Abstract
The invention relates to recombinant fusion proteins comprising a fibrinogenolytic enzyme having an amino acid sequence that is C-terminally and/or N-terminally linked to the amino acid sequence of at least one high-molecular inert stabilization domain with a molecular weight of >50 kDa, for the prevention or treatment of adhesions at tissues or organs, in particular peritoneal adhesions following surgical interventions.