The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 17, 2020
Filed:
Jul. 18, 2014
Scinus Cell Expansion B.v., Bilthoven, NL;
Emerentius Gerardus Roosloot, Bilthoven, NL;
Rudolf Hendrikus Jozef Das, Bilthoven, NL;
Joost Dick De Bruijn, Bilthoven, NL;
Pieter Theo Elias Van Santen, Bilthoven, NL;
SCINUS CELL EXPANSION B.V., Bilthoven, NL;
Abstract
A bioreactor system (A;B) includes a variable volume container () having a flexible outer wall () defining a cell-culture chamber for containing a fluid culture medium, and anchorage dependent cells in suspension. A agitator unit of the system (A;B) is in fluid communication with first, second and third fluid ports (A;B) for performing controlled replenishment of the culture medium in the cell-culture chamber, to admit fresh nutritive culture medium into the cell-culture chamber and for allowing draining of waste culture medium from the cell-culture chamber. The agitator unit further has a roller () for pinching the outer wall of the variable volume container () to thereby increase its a volume that forms the cell-culture chamber, starting from the initial minimum volume area (), and means for gently agitating the cell-culture chamber.