The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 17, 2020
Filed:
Oct. 15, 2014
Applicant:
Sorrento Therapeutics, Inc., San Diego, CA (US);
Inventors:
Zhenwei Miao, San Diego, CA (US);
Gang Chen, San Diego, CA (US);
Tong Zhu, San Diego, CA (US);
Alisher B. Khasanov, San Diego, CA (US);
Yufeng Hong, San Diego, CA (US);
Hong D. Zhang, San Diego, CA (US);
Alexander Chucholowski, Poway, CA (US);
Assignee:
Sorrento Therapeutics, Inc., San Diego, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/65 (2017.01); A61K 47/68 (2017.01); A61K 47/55 (2017.01); C07K 16/28 (2006.01); C07K 16/18 (2006.01);
U.S. Cl.
CPC ...
C07K 16/28 (2013.01); A61K 47/55 (2017.08); A61K 47/65 (2017.08); A61K 47/6801 (2017.08); C07K 16/18 (2013.01);
Abstract
There is disclosed an improved ADC (antibody drug conjugate) type composition having at least two different drug payloads conjugated to a single targeting protein. More specifically, the present disclosure attaches a first drug conjugate to a dual Cysteine residue on a targeting protein and a second drug conjugate with a different drug to a Lys residue on the targeting protein.