The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 17, 2020

Filed:

Jul. 19, 2019
Applicant:

The Texas A&m University System, College Station, TX (US);

Inventors:

Waithaka Mwangi, College Station, TX (US);

Surya Waghela, College Station, TX (US);

Luc Berghman, College Station, TX (US);

Assignee:

The Texas A&M University System, College Station, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/08 (2006.01); C07K 16/28 (2006.01); C07K 16/10 (2006.01); A61K 35/761 (2015.01); A61K 39/42 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/081 (2013.01); A61K 35/761 (2013.01); A61K 39/42 (2013.01); C07K 16/1081 (2013.01); C07K 16/2851 (2013.01); A61K 2039/55522 (2013.01); C07K 2317/31 (2013.01); C07K 2317/622 (2013.01); C07K 2317/626 (2013.01); C07K 2317/76 (2013.01); C12N 2710/10343 (2013.01); C12N 2770/24334 (2013.01); C12N 2810/855 (2013.01);
Abstract

The present invention describes compositions and methods for priming protective immunity in the presence of pre-existing maternal antibody. In some embodiments, the invention contemplates simultaneously masking vaccines to avoid antibody neutralization while targeting those vaccines to specific cell types in order to elicit an enhanced immune response. In other embodiments, vectors that recruit and activate specific antigen-presenting cells may further enhance the efficacy of those immune responses.


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